منابع مشابه
A Practical Guide to Clinical Virology
complement to a standard echocardiographic text, such as the one as written by Dr. Paperbound. Recent advances in molecular biology that allow one to diagnose and study the pathogenesis of viruses along with current strides in rational drug design have provided the clinician with an abundance of facts relevant to the practice of clinical medicine. With so much information scattered throughout t...
متن کاملVirology and Molecular Medicine Session
Mutational activation of cytokine receptors has been described in solid cancers but has not been generally known to drive acute leukemia. We have recently described a subgroup of acute lymphoblastic leukemia characterized by an aberrant expression of the receptor to the cytokine thymic stromal lymphopoietin (TSLP). This receptor is a heterodimer of CRLF2 and IL7RA. In addition to its aberrant e...
متن کاملQuantitative molecular virology in patient management.
The detection of viral genome (that is, viral nucleic acid, either DNA or RNA) has gained enormous importance over the last decade in the diagnosis and management of viral infections and diseases (table 1). Nucleic acid testing (NAT) has proven its superiority over more conventional laboratory techniques in several areas, for example: + for viruses that cannot be cultured in conventional cell c...
متن کاملMolecular techniques for clinical diagnostic virology.
A decade after the first studies were performed it is justifiable to claim that molecular techniques have revolutionised the work of the clinical virology laboratory. Hitherto, the role of the virology laboratory was often a retrospective diagnosis based on virus isolation and serology. Nevertheless, the epidemiological data collected in this way justified the continued activity of clinical vir...
متن کاملMolecular virology and immunology of HIV infection.
Great progress has been made with respect to our understanding of the immunopathogenesis of AIDS and the infectious agent, HIV, that causes the disease. HIV, a human retrovirus with tropism for CD4(+) T cells and monocytes, induces a decrease of T-cell counts, T-cell dysfunction, and, ultimately, immunodeficiency. HIV also causes B-cell dysfunction characterized by polyclonal activation, hyperg...
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ژورنال
عنوان ژورنال: Journal of Medical Genetics
سال: 1993
ISSN: 1468-6244
DOI: 10.1136/jmg.30.6.536-a